Facts & Fiction

Beliefs Held by the Athletic and the Academic Communities On AAS




Beliefs held by athletic community.

What has been demonstrated..

The physician/ academic view and belief.

AAS increase muscle mass, strength, and athletic performance.

Replacement doses of testosterone when administered to hypogonadal men and supraphysiological doses when administered to eugonadal men increase fat-free mass, muscle size, and strength.

Only replacement doses of testosterone when given to hypogonadal men and prepubertal boys have anabolic effects. Supra- physiological doses of testosterone do not further increase muscle mass.

Higher doses of AAS promote greater increases in muscle mass and strength than lower doses; administering more than one androgenic steroid simultaneously (stacking) produces greater increases in muscle mass and strength than any single agent alone.

A linear dose–response relationship exists between testosterone dose and its anabolic effects over a wide range of concentrations extending from subphysiologic to supraphysiologic range.

Beyond the physiologic range, further increases in the dose of AAS would produce no further gains in fat-free mass and muscle strength.

The anabolic and androgenic activities of AAS can be dissociated, so that some derivatives of testosterone have preferentially greater anabolic activity than androgenic activity.

Different androgen- dependent processes have different dose– response relationships.

The anabolic and androgenic activity cannot be dissociated; they are described by the same dose–response relationship.

The anabolic and androgenic effects are mediated through separate mechanisms and thus can be dissociated.

The anabolic effects are likely mediated through an androgen-receptor- mediated mechanism that involves recruitment of tissue- specific coactivators and corepressors.

The anabolic effects are mediated through an androgen-receptor- mediated mechanism.

The effects of AAS administration cause an up-regulation of the skeletal muscle androgen receptor (AR).

AAS administration causes a upregulation of the skeletal muscle and bone androgen receptor (AR).

The effects of AAS administration cause a down-regulation of the skeletal muscle androgen receptor (AR).

HPTA Normalization after AAS cessation is variable and sometimes may never occur.

The severity and duration of ASIH after AAS cessation is unknown and has been reported to take over 2+years.

AAS cessation uniformly results in HPTA normalization within 2 weeks to several months.

Signs & symptoms after AAS cessation are due to inadequate gonadal function.

There is no medical or scientific literature that supports AAS dependency/ addiction. AAS dependency/addiction is not a recognized disease within the ICD-10 or the DSM-IV.

AAS use is associated with adverse health consequences that include chemical dependency/addiction.







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